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mrpD [2019-07-10 09:11:11]
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mrpD [2019-07-10 09:11:11]

H+ transporter subunit of the Na+/H+ antiporter, multiple resistance and pH homeostasis
Locus
BSU31630
Isoelectric point
9.49
Molecular weight
53.21 kDa
Protein length
493 aa Sequence Blast
Gene length
1482 bp Sequence Blast
Function
sodium export
Product
Na+/H+ antiporter subunit
Essential
yes
Synonyms
yufD
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Cellular processes → Transporters → Transporters/ other → Metal ion transporter
  • Cellular processes → Homeostasis → Metal ion homeostasis (K, Na, Ca, Mg) → Sodium uptake/ export
  • Groups of genes → Essential genes
  • Groups of genes → Membrane proteins

    • Gene

    Coordinates
    3,249,761 3,251,242

    Phenotypes of a mutant

  • essential PubMed
  • a mrpD mutant is viable at pH7.4 and sodium concentrations below 80 mM PubMed

    • The protein

    Catalyzed reaction/ biological activity

  • H+ transporter subunit of the Na+/H+ antiporter PubMed

    • Structure

  • 4HE8 (from Thermus thermophilus, 26% identity) PubMed

    • Localization

  • cell membrane (according to UniProt)

    • Expression and Regulation

    Operons

    Genes
    mrpA-mrpB-mrpC-mrpD-mrpE-mrpF-mrpG
    Description
    PubMed
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    Biological materials

    Mutant

  • MGNA-A609 (yufD::erm), available at the NBRP B. subtilis, Japan

    • References

    Reviews

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    Original publications

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